Medically reviewed by Ruffly’s Veterinarian Friends — licensed veterinarians, and pet parents themselves. Last reviewed June 9, 2026. (The reviewing veterinarian will be named here once we have their permission.)
TL;DR: Bravecto for cats comes in two topical (spot-on) versions. Bravecto Spot-On (fluralaner) protects against fleas and ticks for up to 12 weeks. Bravecto Plus (fluralaner + moxidectin) adds heartworm prevention and treats intestinal roundworms and hookworms, and is dosed about every 2 months. Both are applied to the skin at the base of the skull and start killing fleas within about 12 hours. Choose Spot-On for flea/tick only; choose Plus if you also want heartworm and worm coverage. Both are prescription — your veterinarian helps you choose and dose by weight.
Bravecto is a popular, long-lasting parasite preventive for cats. Here’s how the two versions differ and how to pick.
This article is educational and isn’t a substitute for veterinary advice. Your veterinarian will recommend the right product and dose for your cat’s weight and health.
| Bravecto Spot-On (cats) | Bravecto Plus (cats) | |
|---|---|---|
| Active ingredient(s) | Fluralaner | Fluralaner + moxidectin |
| Form | Topical (spot-on) | Topical (spot-on) |
| Protects against | Fleas, ticks | Fleas, ticks, heartworm, roundworms, hookworms |
| How often | Up to every 12 weeks | About every 2 months |
Bravecto Spot-On (fluralaner) kills fleas and ticks and keeps protecting for up to 12 weeks from a single application — fewer doses to remember across the year.
Bravecto Plus (fluralaner + moxidectin) does everything the Spot-On does plus prevents heartworm disease and treats common intestinal worms (roundworms and hookworms). The moxidectin component is why it’s dosed about every two months. It’s the convenient “more-in-one” choice for cats who also need heartworm protection.
Both start killing fleas within about 12 hours and are applied to the skin at the base of the skull.
Heartworm risk varies by region — ask your veterinarian whether your cat needs heartworm prevention. Both are dosed by your cat’s weight, so the right size matters.
Bravecto Spot-On for cats comes in sizes for small, medium, and large cats; Bravecto Plus is also weight-based. Pick the band that matches your cat’s current weight, or check with your vet. Browse all cat medications.
Because parasite prevention is year-round, the per-dose cost matters. You’ll see the price on each product page; our medications are internationally sourced from licensed pharmacies and pharmacist-verified, and shipping is free over $49. A prescription is required — upload it, have us contact your vet, or transfer it.
Bravecto Spot-On (fluralaner) covers fleas and ticks for up to 12 weeks. Bravecto Plus (fluralaner + moxidectin) adds heartworm prevention and treats intestinal worms, dosed about every 2 months.
Bravecto Spot-On protects against fleas and ticks for up to 12 weeks per dose. Bravecto Plus is given about every 2 months.
Only Bravecto Plus (which contains moxidectin) prevents heartworm and treats intestinal worms. The standard Spot-On covers fleas and ticks only.
For cats, Bravecto is a topical (spot-on) solution applied to the skin at the base of the skull.
Yes. You can upload your prescription, have Ruffly contact your vet, or transfer it from another pharmacy.
Compare Bravecto Plus and Bravecto Spot-On for small, medium, and large cats, browse cat medications, or upload a prescription. Always consult your veterinarian.
